ABM HSA Mirna inhibitor

hsa miR miRNA Inhibitor ABM – Antibody-Antibodies

miRNA inhibitors block miRNA regulation of goal gene expression by secure suppression and might knock down native miRNA expression in cells. They can be utilized in miRNA loss-of-function research, miRNA goal web site identification and validation, and miRNA screening experiments. abm‘s Lentivirus miRNA Inhibitors enable for secure, long run expression of miRNA inhibitors out of your cell line.

Key Options

  • We provide a group of miRNA Inhibitors for knockdown of over 5000 miRNAs from human, mouse, and rat.
  • Lentiviral supply for integration of genetic materials into host cells, inflicting secure, long run gene expression.
  • Lentivirus has a broad host vary and might infect each dividing and non-dividing cells, permitting gene supply to all kinds of cell sorts.

For gene regulation and useful research, abm presents a wide range of expression techniques for:

  1. siRNA: effectively categorical any goal siRNA to knockdown any gene with out the necessity to design hair-pin loop shRNA constructions, obtainable in lentivirus, AAV and Adenovirus.
  2. miRNA: inhibit or over-express any miRNA for research of post-transcriptional gene regulation in mammalian techniques utilizing our ready-to-use viral vectors and packaged viruses, in addition to our detection and quantification instruments.
  3. UTR Reporters: quantitatively research a particular miRNA’s regulation of its goal gene utilizing our 3’UTR or 5’UTR platform, all obtainable as a library of premade lentiviral vectors and lentiviruses for any human, mouse or rat gene.
abm hsa mirna inhibitor
abm hsa mirna inhibitor

Background

Non-coding RNAs and particularly microRNAs have been found to behave as grasp regulators of most cancers initiation and development. The intention of our research was to find and characterize the perform of but functionally uncharacterized microRNAs in human breast carcinogenesis.

Strategies

In an unbiased strategy, we utilized a longtime mannequin system for breast most cancers (BC) stem cell formation (“mammosphere assay”) to establish complete miRNome alterations in breast carcinogenesis. Medical samples of BC sufferers had been used to judge the human relevance of the newly recognized miRNA candidates. One promising candidate, miR-1287-5p, was additional explored on its impression on a number of hallmarks of most cancers. The molecular mode of motion was characterised by complete transcriptome evaluation, in silico prediction instruments, miRNA-interaction assays, pheno-copy assays, and drug sensitivity assays.

hsa-let-7c miRNA Inhibitor

MIH01007 2 x 5.0 nmol
EUR 211.2

hsa-let-7d miRNA Inhibitor

MIH01010 2 x 5.0 nmol
EUR 211.2

hsa-let-7e miRNA Inhibitor

MIH01013 2 x 5.0 nmol
EUR 211.2

hsa-let-7g miRNA Inhibitor

MIH01020 2 x 5.0 nmol
EUR 211.2

hsa-let-7i miRNA Inhibitor

MIH01023 2 x 5.0 nmol
EUR 211.2

hsa-miR-1 miRNA Inhibitor

MIH01026 2 x 5.0 nmol
EUR 211.2

hsa-miR-100 miRNA Inhibitor

MIH01027 2 x 5.0 nmol
EUR 211.2

hsa-miR-101 miRNA Inhibitor

MIH01030 2 x 5.0 nmol
EUR 211.2

hsa-miR-103 miRNA Inhibitor

MIH01033 2 x 5.0 nmol
EUR 211.2

hsa-miR-103b miRNA Inhibitor

MIH01037 2 x 5.0 nmol
EUR 211.2

hsa-miR-105 miRNA Inhibitor

MIH01038 2 x 5.0 nmol
EUR 211.2

hsa-miR-106a miRNA Inhibitor

MIH01041 2 x 5.0 nmol
EUR 211.2

hsa-miR-106b miRNA Inhibitor

MIH01044 2 x 5.0 nmol
EUR 211.2

hsa-miR-107 miRNA Inhibitor

MIH01047 2 x 5.0 nmol
EUR 211.2

hsa-miR-10a miRNA Inhibitor

MIH01048 2 x 5.0 nmol
EUR 211.2

hsa-miR-10b miRNA Inhibitor

MIH01051 2 x 5.0 nmol
EUR 211.2

hsa-miR-1178 miRNA Inhibitor

MIH01054 2 x 5.0 nmol
EUR 211.2

hsa-miR-1179 miRNA Inhibitor

MIH01057 2 x 5.0 nmol
EUR 211.2

hsa-miR-1180 miRNA Inhibitor

MIH01058 2 x 5.0 nmol
EUR 211.2

hsa-miR-1181 miRNA Inhibitor

MIH01061 2 x 5.0 nmol
EUR 211.2

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