Is cell-free DNA in spent embryo culture medium an alternative to embryo biopsy for preimplantation genetic testing? a systematic review.
Preimplantation genetic testing (PGT) is more and more used worldwide. It presently entails using invasive strategies, i.e. polar physique, blastomere, trophectoderm biopsy or blastocentesis, to acquire embryonic DNA, with main technical limitations and moral points. Proof means that invasive PGT can result in genetic misdiagnosis within the case of embryo mosaicism, and, consequently, to the […]