Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium

Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium

Intestinal organoids are self-organized three-d (3D) constructions shaped by a single layer of polarized epithelial cells. This revolutionary in vitro mannequin is very related to check physiology of the intestinal epithelium and its function in vitamin and barrier perform. Nonetheless, this mannequin has by no means been developed in rabbits, whereas it could have potential […]

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